Yazar "Değim, Tuncer" için listeleme
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Analysis of DNA damage using the comet assay in female patients treated with phenytoin for epilepsy
Dündaröz, Ruşen; Değim, Tuncer; Değim, Zelihagül; Aydın, Halil İbrahim; Baltacı, Volkan (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-05)Women with epilepsy have been encouraged to consider marriage and child bearing in recent years. Antiepileptic drugs are mostly used such as phenytoin, but its effect on fetus health and its long term effects on DNA have ... -
Effect of long term use of hair dyes on the DNA damage in healthy female subjects
Denli, Metin; Dündaröz, Ruşen; Değim, Zelihagül; Değim, Tuncer; Akın, Mehtap; Baltacı, Volkan (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2002-01)To Date, the toxic effects of hair dyes on DNA have been investigated by several in vivo and in vitro tests and various conflicting results have been reported. To clarify this toxicity, we used "co met assay" which is a ... -
Intraosseous infusion of diazepam using spinaf needle
Dündaröz, Ruşen; Sızlan, Ali; Değim, Tuncer; Yaşar, Mehmet (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-05)Seizure can cause serious brain damage if it prolongs. It is general need to terminate seizure as soon as possible using anticonvulsant drugs via intravenous (IV) route. But, it is very difficult to achieve secure IV line ... -
Isolated perfused rabbit ear model for the assessment of transdermal drug delivery
Büyükafşar, Kansu; Demirel, Emine; Özoğul, Candan; Akay, Cemal; Değim, Tuncer (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2003-01)Isolated perfused rabbit ear model together with full thickness human skin and PDMS membrane were used to investigate the penetration properties of naproxen and the enhancer activity of capsaicin. The effect of capsaicin ... -
The use of bone injection gun in the loading of phenytoin an experimental study in dogs
Dündaröz, Ruşen; Sızlan, Ali; Değim, Tuncer; Yaşar, Mehmet; Denli, Metin; Özışık, Tahir (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-01)Status epilepticus can cause irreversible cerebral injury if it prolongs and it is essential to terminate seizure rapidly. Antiepileptic drugs should be introduced to the patients intravenously (IV), but it is almost ...
