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Analysis of DNA damage using the comet assay in female patients treated with fluoxetine against depression
Dilbaz, Nesrin; Dündaröz, Ruşen; Değim, Zelihagül; Aydın, Halil İbrahim; Denli, Metin; Baltacı, Volkan (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-01)Depression during pregnancy is not uncommon. One of the main concern with psychotropic drugs during pregnancy is teratogenicity. Although fluoxetine is one of the most frequently prescribed antidepressant, its safety in ... -
Assessment of DNA damage induced by carbamazepine in epileptic women
Dündaröz, Ruşen; Aydın, Halil İbrahim; Güngör, Tayfun; Gök, Faysal; Denli, Metin; Baltacı, Volkan (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-01)Pregnancy is one of the most difficult problems to be solved in epileptic female patients. The main concern with antiepileptic drugs (AEDs) during pregnancy is the Teratogenicity. Carbamazepine (CBZ) is one of the most ... -
Effect of long term use of hair dyes on the DNA damage in healthy female subjects
Denli, Metin; Dündaröz, Ruşen; Değim, Zelihagül; Değim, Tuncer; Akın, Mehtap; Baltacı, Volkan (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2002-01)To Date, the toxic effects of hair dyes on DNA have been investigated by several in vivo and in vitro tests and various conflicting results have been reported. To clarify this toxicity, we used "co met assay" which is a ... -
The use of bone injection gun in the loading of phenytoin an experimental study in dogs
Dündaröz, Ruşen; Sızlan, Ali; Değim, Tuncer; Yaşar, Mehmet; Denli, Metin; Özışık, Tahir (Afyon Kocatepe Üniversitesi, Kocatepe Tıp Dergisi, 2001-01)Status epilepticus can cause irreversible cerebral injury if it prolongs and it is essential to terminate seizure rapidly. Antiepileptic drugs should be introduced to the patients intravenously (IV), but it is almost ...