Functional anatomy of the carpal region in sprague dawley strain rats

Abstract

Dating back to 1830, Rattus norvegicus holds the distinction of being one of the first mammals domesticated for use in scientific researches. While detailed anatomical information about the human carpal region is available, such information is lacking for rats. The current study aims to resolve the ambiguity in the literature by determining which bones constitute the carpal bones of Sprague Dawley starin rats ,the number and arrangement of these bones. Additionally, the study seeks to elucidate how the carpal tunnel, which is important in translational anatomy, is formed and which structures pass through it.In the study, seven 9-month-old female Sprague Dawley strain rats carpal regions were examined, macroscobically, morphometrically and radiologically.The carpal bones of Sprague Dawley rats were examined and found to be arranged in two rows: proximal and distal. A total of six carpal bones were identified, two in the proximal row and four in the distal row. The formation of the carpal tunnel in rats has been observed as follows. It is noted to form between the distal end of the antebrachium and the distal carpal bones. Compared to human and rat carpal bones and carpal tunnel, both of the structures are quite different each other.Therefore, it has been concluded that these rats are unsuitable for experimental surgical models, especially those focusing on the carpal region.